Antibody Subunit Analysis on a High-Resolution Quadrupole-orbitrap Mass Spectrometer
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Mass spectrometry plays a vital role in the characterization of monoclonal antibodies (mAbs) during biopharmaceutical development and manufacturing. Techniques such as intact mass analysis and peptide mapping are now standard tools for monitoring structural integrity and product consistency. In addition, subunit analysis offers complementary insights with minimal sample preparation, providing a streamlined approach to mAb characterization.